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What Is OLIF Surgery and Why Should You Care?

Spine Problems

Spine Care

17 July, 2025

When back pain or leg pain persists and disrupts your everyday life, searching for safe, effective solutions feels like a journey. You might have heard of Oblique Lateral Interbody Fusion (OLIF) surgery. OLIF is a surgical procedure that is designed for “long-term relief and stability” of the spine. If you are contemplating OLIF surgery or just want to learn more about this new spinal procedure, you are in the right place. Let's discuss OLIF surgery; the advantages of OLIF; the OLIF spine surgery procedure itself; and the recovery, and we will do this in layman's terms.

Oblique Lateral Interbody Fusion (OLIF) is a spinal fusion surgery that works in the lumbar (lower) spine. Traditional spinal fusion surgeries often require significant disruption and cutting of back muscles, bones and manipulation of spinal nerves.  OLIF surgery uses a different approach: the surgeon gains access to the spine through a small incision on the left side of the abdomen and carefully moves through intermuscular planes to get to the spine.

spinal cord

Understanding the OLIF Advantage: Less Pain, Faster Recovery, Stronger Results

1. Less risk, More Effective:

By avoiding cutting spinal muscles, bones and nerves, OLIF spares you excessive pain, muscle damage, and scar tissue formation. A big advantage of this is  “significantly reduced risk of spinal nerve damage”.

2. Faster Recovery:

Most patients can stand and “walk the next day” after surgery. The technique often translates to a hospital stay of 4-5 days, which includes supervised physiotherapy. Many patients return to daily activities in the next few weeks.

3. Better Correction & Fusion Rates, Reduced risk of future spinal surgeries:

A major benefit of the OLIF approach is the ability to insert a large inter-body cage, which  “restores spinal height and natural balance, encourages strong bone fusion, reduces risk of future spinal surgeries”. OLIF spine surgery allows for excellent correction of spinal deformities, such as scoliosis or flat-back syndrome.

4. Minimal Blood Loss & Less Post-Op Pain:

Thanks to the nature of the approach—and the use of advanced imaging like fluoroscopy—OLIF surgery is associated with “minimal blood loss and lower pain scores post-operatively”.

Is OLIF Right for You? Who Can Truly Benefit From This Advanced Spine Surgery

OLIF spine surgery is typically recommended when other conservative treatments like physical therapy, medications, and injections haven’t worked. This approach is especially effective for these lumbar spine conditions:

  • Degenerative disc disease

  • Herniated discs

  • Spinal stenosis (narrowing of the spinal canal)

  • Scoliosis and other spinal deformities

  • Spondylolisthesis (slipping of one vertebra over another)

  • Spinal instability

Not everyone is a candidate; the decision is always individualised, based on detailed imaging and a thorough evaluation by a spinal specialist.

A Closer Look: Step-by-Step Walkthrough of the OLIF Surgery Procedure

1. Preparation & Anaesthesia:

The patient is given general anaesthesia and is positioned on their side to start with.

2. Surgical Approach:

A small incision—typically around 6-8 cm—is made on one side of the abdomen. Using advanced imaging, the surgeon gently moves aside the abdominal muscles and tissues. The “approach avoids major back muscles, bones and nerves”.

3. Accessing the Spine:

Care is taken to reach the damaged disc space without disturbing surrounding vital structures. Special instruments are used to remove the degenerated disc and clean the disc space.

4. Insertion of the Graft/Cage:

Through this corridor, a large cage (often made of titanium or medical-grade plastic) filled with a lot of bone graft is inserted in place of the removed disc, "restoring disc height and realigning the spine”. The graft encourages the adjacent vertebrae to fuse, creating a stable, pain-free segment.

5. Stabilisation:

The patient is then turned prone, and additional screws and rods are inserted from the back to support the spine further during healing.

6. Closure:

The incision is closed with careful attention to minimise scarring. The time for the procedures depends on the number of spinal levels being treated.

Real Stories of Healing: Transformative OLIF and ALIF Surgeries

Behind every successful surgery is a life reclaimed, a family relieved, and a sense of independence restored. At Manipal Hospitals, Dwarka, our expert spine team has helped hundreds of patients rediscover comfort and confidence. Here are three remarkable journeys from our practice:

Case 1:

 

OLIF and ALIF surgery

A 70-year-old woman came to us six months ago, suffering from spinal slip and stenosis that left her with significant leg weakness and loss of bladder and bowel control. She underwent an OLIF surgery—a procedure that stabilises the spine and brings back natural balance with less risk to nerves and excellent fusion rates. Today, her mobility and bladder/bowel functions are fully restored, and she’s enjoying her daily life once more.

Case 2:

OLIF and ALIF surgeries

 

For more than five years, a 52-year-old woman endured severe back and leg pain due to spinal listhesis and disc loss. We treated her using a combination of ALIF (Anterior Lumbar Interbody Fusion) and OLIF lumbar surgery techniques. By restoring her spinal alignment and correcting her lordosis, her back and leg pain has resolved—and she’s back to doing what she loves, pain-free.

Case 3: 

                                                                       olif and alif surgery                                                               

Complex spinal problems require a tailored approach. A 52-year-old woman who had previously undergone spine surgery in 2021 returned to us with a failed outcome called distal junction failure, as her spine tried to compensate for lost balance. Through revision of OLIF lumbar surgery at two levels, we were able to restore her natural lumbar lordosis. Six months on, she reports renewed comfort and satisfaction with her quality of life.

Choose Manipal Hospitals Global: Where Hope Meets Expertise

These actual results of real patients are a testament to why so many rely on Manipal Hospitals Global for their spinal health. We offer advanced surgical techniques, OLIF and ALIF are surgeries that only some of the most experienced spine surgeons in India perform. They prioritise patients' recovery, safety, and well-being “for the long term”. If you are suffering from back pain or have a complicated spinal issue, let us help you get back to being strong and confident, with compassionate care and proven competence throughout.

Reviewed By:

Dr. Nikhil Jain

Manipal Hospitals, Delhi

FAQs

OLIF spine surgery generally takes about 1.5 to 2 hours for each part of the surgery. The surgery is usually performed in two parts such as the lateral position to access the spine and the prone position to place screws and rods in the spine. The full surgery generally takes about 4 to 6 hours total. If multiple levels are being operated on, it may increase the time of the surgery minimally, but new techniques have limited increases in time.
 

Due to the minimally invasive nature of OLIF surgery, recovery generally happens faster than with traditional spine surgeries. Depending on your job duties and your body's healing, it is realistic for you to return to light duties or desk duties in about 4 to 6 weeks. Physically demanding jobs that require lifting, may take longer and you may take 8 to 12 weeks or more to return to work. Our surgeon at Manipal Hospitals Global will provide you personal recommendations based on your recovery.
 

Common risks include:

  • Infection

  • Nerve or vascular injury

  • Blood clots (DVT)

  • Nonunion of the spinal bones

However, OLIF is less invasive than traditional spine surgeries, lowering these risks.
Proper pre-operative assessment and post-operative care further minimise complications.
 

Although OLIF surgery is performed minimally invasive and seeks to alleviate surgical pain, patients can anticipate discomfort following the procedure. Pain levels are different for everyone, but many patients find that after surgery, one is left with less pain compared to traditional open-back surgeries. Pain typically decreases dramatically within a few days to weeks of the procedure. For the patient's comfort during recovery, patients always receive a post-operative pain control plan with medications and PT to alleviate pain.
 

Whether or not you qualify for OLIF surgery depends primarily on your spinal condition, anatomy, physical health, and whether previous non-operative management options have not been successful. Your spine specialist will provide more information to help you determine the optimal solution for your condition.
 

The OLIF surgery recovery time varies from person to person and generally is between 6 to 12 weeks for basic functional recovery. The recovery for a full recovery with spinal fusion may take anywhere from 6 months to a year before returning to high-impact activities.